Arjun is from Royal Gujjar community. His parents are Gwen and Amarjeet Rampal. Arjun and his younger sister attended the prestigious Kodaikanal International School located in the Palani Hills,Tamil Nadu, where his mother was a teacher. One of his cousins, Kim Sharma, is an actress and appeared with him in the film Yakeen. He married former Miss India and supermodel Mehr Jesia and they have two daughters, Mahikaa, born on January 17, 2002 and Myra, born June 2005. Arjun Rampal was discovered in a Mumbai discotheque by designer, Rohit Bal. He was a student of prestigious Hindu College, Delhi then.
Arjun became Rohit's protégé and promoted him to the extent that he became one of India's most sought after male supermodels. His debut movie - Moksha was released in 2001 and was directed by Ashok Mehta. However, this film was released after his second film, Pyaar Ishq Aur Mohabbat, in which he appeared with Sunil Shetty and Aftab Shivdasani. Although both films did not perform at the box office his performances in both films was lauded by critics. In 2002, he won the Award of the International Indian Film Academy for Face of the Year.
Since his debut, he has worked steadily in films such as Aankhen (2002), Dil Hai Tumhaara (2002), Yakeen (2005) and Ek Ajnabee (2005). He has also appeared in the Temptations 2004 concert with stars Shahrukh Khan, Rani Mukerji, Saif Ali Khan, Preity Zinta, and Priyanka Chopra. In 2006 he made a guest appearance in the multi-starrer Kabhi Alvida Naa Kehna and played a supporting role in Don - The Chase Begins Again which is a remake of the 1978 Amitabh Bachchan starrer Don. Rampal donned the role of Jasjit who was played by the veteran actor Pran in the original movie.